ReproSil Chiral-BM

Ajánlatkérés
Cikkszám: r65.bm. (5µm)
Gyártó: Dr. Maisch

Leírás és Paraméterek

Cellulose-Based Chiral Phase with Tris-Benzoate Coating for Enantioselective Normal-Phase Chromatography

ReproSil Chiral-BM is a silica-based HPLC stationary phase coated with tris-benzoate cellulose, specifically developed for enantioselective separations under normal-phase conditions. The cellulose tris-benzoate chiral selector enables multiple molecular interaction mechanisms – including hydrogen bonding, dipole–dipole, and π–π interactions – providing high chiral recognition and excellent resolution for a broad variety of racemic compounds.

The high-purity, mechanically stable spherical silica ensures robust performance, high reproducibility, and long column lifetime. The benzoate-substituted cellulose derivative offers a unique selectivity profile that complements other chiral stationary phases, making ReproSil Chiral-BM particularly valuable in method development for pharmaceutical and chemical enantioseparations.

Designed for both analytical and preparative use, this phase provides reliable performance in the separation of chiral pharmaceuticals, intermediates, and fine chemicals under standard normal-phase mobile phase conditions (e.g., n-hexane/alcohol mixtures).

ReproSil Chiral-BM combines the proven chiral selectivity of cellulose tris-benzoate with the robustness of high-purity silica – the dependable choice for precise and reproducible enantioselective separations in normal-phase chromatography.

Attractive Alternative to CHIRALCEL® OB-H (Daicel®).

Particle Size
  • 5 µm
Pore Size 1 000 Å
Surface Area 30 m²/g
Phase/Modification Tris-Benzoat-Cellulose
Particle Type
Separation Mode
Endcapping No
pH Range 2 to 8

Key Features:

  • Silica-based stationary phase coated with tris-benzoate cellulose

  • Developed for enantioselective separations in normal-phase chromatography

  • High chiral recognition through hydrogen bonding, π–π, and dipole–dipole interactions

  • Distinct selectivity profile complementary to amylose-based phases

  • Excellent mechanical stability and reproducibility

  • Suitable for analytical and preparative chiral HPLC applications

Typical Applications:

  • Enantioselective separation of chiral pharmaceuticals and intermediates

  • Analysis of racemic fine chemicals and natural products

  • Method development in chiral HPLC under normal-phase conditions

  • Quality control and purity assessment of optically active compounds