ReproSil Chiral-AM-R

Ajánlatkérés
Cikkszám: r63.amr. (3µm) | r65.amr. (5µm) | r60.amr. (10µm)
Gyártó: Dr. Maisch

Leírás és Paraméterek

Amylose-Based Chiral Phase for Enantioselective Reversed-Phase Chromatography

ReproSil Chiral-AM-R is a silica-based HPLC stationary phase coated with tris-(3,5-dimethylphenyl)carbamate amylose, specifically developed for enantioselective separations under reversed-phase conditions. This chiral amylose derivative enables multiple molecular interactions – such as hydrogen bonding, dipole–dipole, and π–π interactions – which result in excellent chiral recognition and high enantioselectivity for a wide variety of racemic compounds.

In contrast to the normal-phase version, ReproSil Chiral-AM-R is optimized for aqueous and polar mobile phases, providing high stability and reproducible retention under reversed-phase conditions. The phase is built on high-purity spherical silica, ensuring outstanding mechanical robustness and consistent performance even in gradient or high-pressure operation. ReproSil Chiral-AM-R is ideal for pharmaceutical, biochemical, and academic laboratories performing enantioselective analysis, method development, or quality control of chiral active ingredients and intermediates.

ReproSil Chiral-AM-R combines amylose-based chiral selectivity with reversed-phase compatibility – the dependable choice for efficient and reproducible enantioselective separations under aqueous chromatographic conditions.

Attractive alternative to CHIRALPAK® AD-RH (Daicel®).

Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 1 000 Å
Surface Area 30 m²/g
Phase/Modification Tris-(3,5-dimethylphenyl)carbamat-Amylose
Particle Type
Separation Modes
USP Code
Endcapping No
pH Range 2 to 8

Key Features:

  • Silica-based stationary phase coated with tris-(3,5-dimethylphenyl)carbamate amylose

  • Optimized for enantioselective separations in reversed-phase chromatography

  • Excellent chiral recognition via hydrogen bonding, dipole–dipole, and π–π interactions

  • Stable and reproducible under aqueous and polar mobile phase conditions

  • Suitable for analytical and preparative chiral HPLC applications

Typical Applications:

  • Enantioselective separation of chiral pharmaceuticals and intermediates

  • Quality control and purity testing of optically active compounds

  • Method development for chiral reversed-phase HPLC

  • Analysis of chiral biomolecules and polar organic compounds