Leírás és Paraméterek
Amylose-Based Chiral Phase with (S)-α-Methylbenzyl Carbamate for Enantioselective Reversed-Phase Chromatography
ReproSil Chiral-AMS-R is a silica-based HPLC stationary phase coated with tris-(S)-α-methylbenzyl carbamate amylose, specifically developed for enantioselective separations under reversed-phase conditions. The chiral amylose derivative, substituted with (S)-α-methylbenzyl carbamate groups, provides a distinct stereochemical recognition pattern, enabling high enantioselectivity and resolution for a wide variety of chiral analytes.
Optimized for aqueous and polar mobile phases, ReproSil Chiral-AMS-R offers stable retention behavior, excellent reproducibility, and robust performance in gradient and isocratic operation. The phase is built on high-purity, mechanically stable spherical silica, ensuring long column lifetime and consistent results even under routine analytical conditions. With its combination of chiral selectivity and reversed-phase compatibility, ReproSil Chiral-AMS-R is ideally suited for pharmaceutical, biochemical, and academic laboratories focusing on chiral separations of polar and water-soluble compounds.
ReproSil Chiral-AMS-R combines the stereochemical selectivity of (S)-α-methylbenzyl carbamate amylose with reversed-phase compatibility – the reliable choice for precise and reproducible enantioselective separations in aqueous chromatographic systems.
Attractive alternative to CHIRALPAK® AS-RH (Daicel®).
| Particle Sizes |
|
|---|---|
| Pore Size | 1 000 Å |
| Surface Area | 30 m²/g |
| Phase/Modification | Tris-(S)-α-methylbenzylcarbamat-Amylose |
| Particle Type | |
| Separation Modes | |
| Endcapping | No |
| pH Range | 2 to 8 |
Key Features:
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Silica-based stationary phase coated with tris-(S)-α-methylbenzyl carbamate amylose
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Designed for enantioselective separations under reversed-phase conditions
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Excellent chiral recognition and high resolution for diverse analytes
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Stable and reproducible performance with aqueous and polar mobile phases
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Suitable for analytical chiral HPLC applications
Typical Applications:
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Enantioselective separation of chiral pharmaceuticals and intermediates
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Analysis of polar and water-soluble chiral compounds
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Quality control and purity testing of optically active substances
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Method development and research in pharmaceutical and biochemical laboratories