ReproSil Chiral-AM

Ajánlatkérés
Cikkszám: r63.am. (3µm) | r65.am. (5µm) | r60.am. (10µm) | r620.am. (20µm)
Gyártó: Dr. Maisch

Leírás és Paraméterek

Amylose-Based Chiral Phase for Enantioselective Normal-Phase Chromatography

ReproSil Chiral-AM is a silica-based HPLC stationary phase coated with tris-(3,5-dimethylphenyl)carbamate amylose, specifically developed for enantioselective separations in normal-phase chromatography. The amylose derivative provides multiple interaction mechanisms – including hydrogen bonding, dipole – dipole, and π–π interactions – which enable excellent chiral recognition and high resolution for a broad range of racemic compounds.

The high-purity spherical silica ensures mechanical stability and reproducibility, while the optimized coating process guarantees strong phase adherence and consistent enantioselectivity. ReproSil Chiral-AM is suitable for analytical and preparative separations in pharmaceutical, chemical, and biochemical research, particularly in method development and quality control of chiral active ingredients and intermediates.

ReproSil Chiral-AM combines amylose-based chiral recognition with robust silica stability – the reliable choice for precise and reproducible enantioselective separations in normal-phase chromatography.

Attractive alternative to CHIRALPAK® AD-H (Daicel®) and Lux Amylose-1 (Phenomenex™).

Specifications

Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
  • 20 µm
Pore Size 1 000 Å
Surface Area 30 m²/g
Phase/Modification Tris-(3,5-dimethylphenyl)carbamat-Amylose
Particle Type
Separation Modes
USP Code
Endcapping No
pH Range 2 to 8

Key Features:

  • Silica-based stationary phase coated with tris-(3,5-dimethylphenyl)carbamate amylose

  • Designed for chiral separations under normal-phase conditions

  • Excellent enantioselectivity through multiple interaction mechanisms

  • High reproducibility and mechanical stability

  • Suitable for analytical and preparative chromatography

Typical Applications:

  • Enantioselective separation of chiral pharmaceuticals and intermediates

  • Quality control and purity testing of optically active compounds

  • Method development for chiral HPLC in research and production

  • Analysis of chiral agrochemicals and fine chemicals